INTERLEUKIN-12 ELICITS A NON-CANONICAL RESPONSE IN B16 MELANOMA CELLS TO ENHANCE SURVIVAL

Abstract Background Oncogenesis rewires signaling networks to confer a fitness advantage to malignant cells.For instance, the B16F0 melanoma cell model creates a cytokine sink for Interleukin-12 (IL-12) to deprive neighboring cells of this important anti-tumor immune signal.While a cytokine sink provides an indirect fitness advantage, does IL-12 pr

In the aspect of information storage, text assumes a central role, necessitating streamlined and effective methods for swift retrieval.Among various text representations, the vector form stands out for its remarkable efficiency, especially when dealing with expansive datasets.Arranging words that are similar in meaning close to each other in the ve